User:Herb5902/r+ alpha lipoic acid
From WikiAlpha
Benefits:
- HIV reverse transcriptase inhibitor
- α-lipoic acid induces apoptosis in human colon cancer cells
- Activates AMPK
- Reduces insulin resistance
- Modulates Nrf2 transcription.
- Suppresses renal oxidative stress and inflammation.
- Enhances sirtuin 1 deacetylase activity
- increases adipose triacylglycerol lipase expression
- decreases fatty acid synthase abundance
- Prevents renal tubular cell apoptosis, fibrosis, and diabetic nephropathy
- Adults can take up to 2,400 mg without harmful side effects
- Improves Intestinal Dysmotility (does it cause diarrhea?)
- Colitis
-
Streptococcus
Side effects:
- Hepatotoxic
-
Flatulence
Diabetic nephropathy
In addition to activating AMPK and reducing insulin resistance, alpha lipoic acid modulates Nrf2 transcription, suppresses renal oxidative stress, reduces inflammation, enhances sirtuin 1 deacetylase activity, increases adipose triacylglycerol lipase expression, and decreases fatty acid synthase abundance. It also prevents renal tubular cell apoptosis, fibrosis, and diabetic nephropathy.